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A few days after his 74th birthday, Don Stivers received his dream gift -- a new heart.

"I was born with a very lousy heart," he explained. "Growing up, I decided I was going to overcome it and go to the Olympics and be a strong boy. And so everything I did was against doctors' orders. They said don't run, don't do this, but I did anyway, and I would turn blue and pass out, and my mother...

Robert Chelsea needed a new face, having lost most of his in a horrific Los Angeles traffic accident years ago.

But Chelsea is Black, and the process to give him the first-ever face transplant wound up posing novel challenges for his doctors, according to a new report.

It took four times as long to find Chelsea a suitable donor than it typically does for white patients, doctors said...

People with kidney failure related to sickle cell disease are less likely to receive a transplant than those without sickle cell disease, but it could be life-saving for them, a new study finds.

Sickle cell disease is a risk factor for kidney failure, and adults with sickle cell-related kidney failure who are on long-term dialysis have high rates of early death.

Kidney transplant is...

Despite widespread efforts to increase access and awareness, new research shows there's been virtually no change in the number of people on waiting lists for potentially lifesaving kidneys over the past two decades.

For their study, scientists analyzed information on more than 1.3 million adults with kidney failure listed in the United States Renal Data System from 1997 to 2016, and found...

Here's some good news for people who've had solid organ transplants and have weakened immune systems: mRNA coronavirus vaccines are safe for these vulnerable folks, new research shows.

The study included 187 transplant recipients who received an initial dose of either the Moderna or Pfizer mRNA vaccines between Dec. 16, 2020 and Jan. 16, 2021.

The participants, median age 48, were r...

Joe DiMeo's life changed forever when he fell asleep at the wheel on U.S. Route 22 in New Jersey on July 14, 2018.

The horrific crash left him with third-degree burns on 80% of his body and a grim prognosis.

Now, more than two years later, DiMeo, 22, is the recipient of the world's first successful double hand and face transplant, and on the road to recovery.

The historic surg...

Heart transplants may be particularly risky for young Black Americans, with new research suggesting they are twice as likely to die after they receive their new organ.

To reach that conclusion, researchers analyzed the outcomes of nearly 23,000 adults, aged 18 to 80, who had a heart transplant in the United States between 2005 and 2017.

Compared to other heart transplant recipi...

Frailty may explain why women awaiting a liver transplant are more likely than men to become too sick for a transplant or die before transplantation, a new study suggests.

Exercise and a healthier diet may help narrow that gender gap, researchers say.

For the study, researchers followed more than 1,400 patients with cirrhosis awaiting a liver transplant from nine U.S. transpla...

Nurses are known for being kind, caring and sympathetic, but Brianna Fogelman brings an uncommon empathy to her nursing job at Johns Hopkins Medicine in Baltimore.

Fogelman, 27, underwent a double lung transplant last year to treat a rare lung disease and returned this fall to work in the same hospital where she received her life-changing surgery.

"I understand how it feels to have ...

Case studies and autopsy results are confirming that, in some cases, COVID-19 can cause such severe lung damage that patients require a lung transplant to survive.

In a new study, researchers in Chicago analyzed discarded tissue from COVID-19 patients who had lung transplants and from patients who died of the disease. They found that COVID-19 can destroy the "fundamental framework" of th...

About one in five Americans waiting for a liver transplant dies before getting the organ. Their odds might be better if more people knew they could donate a portion of their liver in a process called living liver donation.

Doctors at the Mayo Clinic in Rochester, Minn., want to raise awareness of these living liver transplants.

"About 12,000 to 13,000 people are on the liver transp...

U.S. and Canadian restrictions on cornea donations from gay and bisexual men prevent thousands of vision-restoring transplants and need to be changed, researchers say.

A corneal transplant can cure some forms of blindness and visual impairment. The United States bans men from donating if they have had gay sex in the past five years; Canada has a 12-month restriction.

The sa...

Transplants of organs from dead donors haven't slowed during the coronavirus pandemic, but living donor transplants remain suspended in many places, an expert says.

Dr. Fauzia Butt, a transplant surgeon at Penn State Health Milton S. Hershey Medical Center in Hershey, Pa., also said that organ donation and transplant surgery are safe during the pandemic.

"We've put protocols...

Hearts donated by severely obese donors aren't more risky for recipients than hearts from people who aren't obese, a new study indicates.

"These findings were somewhat surprising because the severely obese donors did tend to have more medical problems, such as diabetes and high blood pressure, than the non-obese donors," said study author Dr. Leora Yarboro. She's an associate professo...

New hepatitis C medications are allowing people to receive a kidney transplant from a deceased donor who had the liver disease -- a strategy aimed at getting more lifesaving organs to patients languishing on waitlists.

Two new studies are highlighting the promise of the approach, showing that if patients are given the drug Mavyret, they can safely receive the kidneys and the organs fu...

Two coronavirus patients who became so sick that double lung transplants were their only chance for survival are now recovering from their harrowing journeys, their doctors report.

Mayra Ramirez, 28, and Brian Kuhns, 62, are the first known COVID-19 cases in the United States where such a drastic procedure was tried, according to their doctors at Northwestern Medicine in Chicago.

...

A young COVID-19 survivor received a double-lung transplant to save her life in what's believed to be the first such surgery in the United States, Northwestern Medicine doctors report.

Following her infection, the Hispanic woman in her 20s suffered irreversible lung damage and had to be put on a life-support machine that does the work of the heart and lungs.

"A lung transpla...

The coronavirus pandemic has affected all areas of medical care, and a new study finds it has delayed potentially life-saving organ transplants.

Across the United States, transplants from deceased donors dropped 51% from early March to early April, amid the COVID-19 outbreak, the researchers found. In France, meanwhile, those procedures plummeted 91%.

Experts said th...

Because people who receive a donor kidney are often on immune-suppressing medications, they're at extremely high risk of dying if COVID-19 strikes, a new report warns.

The study, from doctors at Montefiore Medical Center in hard-hit New York City, looked at outcomes for 36 kidney transplant patients diagnosed with COVID-19 between March 16 and April 1.

Nearly a third of thes...

One of the few bright spots in the COVID-19 pandemic has been the perception that children are mostly spared from its worst effects. But what about kids already at risk of contracting serious infections due to a compromised immune system? Do they have the same protection?

"One group we always worry about when it comes to viral illnesses is immunocompromised children," said Dr. Reggie...

It was 12 years ago that a German patient was seemingly cured of HIV. Now doctors in the United Kingdom believe they've finally duplicated that success, this time in a 40-year-old Englishman.

Adam Castillejo was known until recently only as the "London patient." Now, after surviving years of grueling treatments, he says he sees himself as an "ambassador of hope" for others.

...

Doctors thought they had a fairly common scenario in front of them: A patient with advanced liver disease who needed help for her alcohol abuse. Then they discovered her own bladder was making the alcohol.

The doctors, at the University of Pittsburgh, say it's a previously unrecognized variant of so-called auto-brewery syndrome. ABS, which has been reported sporadically over the years...

The risks faced by U.S. bone marrow transplant patients have dropped sharply, a new study shows.

While this type of transplant can be lifesaving for patients with blood cancers (such as leukemia) and other diseases, there are potentially life-threatening risks, the researchers noted.

But the new analysis of 1,148 patients who had bone marrow transplants at the Seattle Cancer...

Many of the donor kidneys that are discarded each year in the United States could instead be effectively transplanted, a large new study suggests.

At issue are kidneys from deceased donors that are acutely injured. Right now in the United States, about 30% of those organs are discarded, rather than being given to patients on transplant waitlists.

But the new study found ...

Researchers report they have developed a machine that can repair injured livers and keep them alive outside the body for up to a week.

They said the machine could one day increase the number of livers available for transplant and save the lives of many people with severe liver diseases or cancer.

Until now, it was only possible to store livers safely outside the body for a f...

One-year survival rates are similar for transplant patients who receive a heart from a donor with hepatitis C or one without the infectious virus, a new study finds.

The researchers suggest that using hearts from donors with hepatitis C, a viral infection of the liver, may be safe and could help reduce a U.S. organ shortage.

The study included nearly 7,900 adults with heart ...

Racial bias among health care providers limits black Americans' odds of receiving a heart transplant, a new study finds.

Researchers asked 422 U.S. physicians, nurses and other hospital decision-makers to review the hypothetical cases of black men and white men with heart failure and to decide if the patients should be referred for a heart transplant.

The hypothetical cases ...

A U.S. veteran who received a total penis and scrotum transplant last year is faring better than anyone expected, his doctors say.

In March 2018, the soldier -- who was severely wounded after stepping on a bomb in Afghanistan -- underwent the world's first total penis and scrotum transplant. A team of 11 surgeons at Johns Hopkins University in Baltimore performed the 14-hour procedure...

Many U.S. transplant centers accept less-than-ideal kidneys from deceased donors, but their willingness to use such organs varies widely.

That's the conclusion of a study that examined the use of deceased-donor kidneys at 182 transplant centers nationwide.

Researchers found big differences among them in use of less-than-ideal kidneys that was not fully explained by the size ...

There's good news for people with HIV who get a kidney from a donor who also has HIV: A new study reports high five-year survival rates.

"A growing number of people with HIV have a need for kidney transplants. Unfortunately, these gifts of life are too often in short supply," said Dr. Anthony Fauci, director of the U.S. National Institute of Allergy and Infectious Diseases.

In a finding that suggests money may sometimes guide whether someone gets a new kidney, researchers report that patients at U.S. for-profit dialysis centers are less likely to receive a transplant.

"For-profit dialysis facilities have a higher profit margin when they have more patients on dialysis," while nonprofit centers don't have "the same emphasis on profit margins," explained s...

Kidneys from donors with the hepatitis C virus (HCV) are routinely used in kidney transplants in the United States and function well in the first year after transplantation, a new study says.

The findings provide reassurance that the use of HCV-infected kidneys for transplantation is safe and effective, said Dr. Vishnu Potluri and Dr. Peter Reese of the University of Pennsylvania, and...

A new "supercooling" technique can triple the length of time a donor liver can be preserved before transplantation, researchers say.

The new method -- which cools the liver to 21.2 degrees Fahrenheit without freezing it -- could make significantly more livers available for transplant.

Currently, a donor liver is stored on ice in a preservative solution at temperatures betwee...

Many Americans who die waiting for a kidney transplant actually had donor organs offered to them multiple times -- but their transplant center declined them.

That's the finding of a new study of over 280,000 U.S. patients who were on kidney transplant waitlists between 2008 and 2015.

It may come as a surprise to anyone who's assumed that when patients languish on waitlists, ...

When it comes to using kidneys from deceased donors, the United States might want to follow France's example.

That's according to new research that found kidneys from older donors are much more likely to be used for transplants in France, and if more of those "lower-rated" kidneys were used in the United States, tens of thousands more Americans would receive a kidney transplant.

...

Scientists say they have taken an important step forward in creating 3-D printed hearts -- with the ultimate goal of making replacement tissue for organs and body parts damaged by disease or injury.

The 3-D printing process builds three-dimensional objects based on a computer model. Unlike traditional printing onto a flat surface, the machines churn out various materials -- plastics, ...

Doctors at the Cleveland Clinic announced that they've achieved a first in North America: delivering a baby from a uterus that had been transplanted from a deceased donor.

The healthy baby girl was delivered by C-section in June. This is only the second time such a delivery has happened worldwide, the first having occurred in Brazil in December.

"We couldn't have asked for a...

Not so long ago, face transplants were considered futuristic medicine, but a new report shows these patients are better off years after their groundbreaking operations.

Six people who received full or partial face transplants have since had significant restoration of feeling and movement, along with an improved quality of life, surgeons say.

"From the data, you can see the c...

Severely damaged lungs can be regenerated to be suitable for transplantation, researchers say.

A transplant is the only lifesaving treatment for people with end-stage lung disease, but donor organs are in short supply.

Up to 80 percent of donor lungs are rejected due to serious but potentially reversible injuries. Researchers hope to increase the supply of lungs available fo...

Viruses and bacteria are the culprits behind the infectious diseases that plague humans. Researchers recently turned one against the other, using viruses to wipe out a potentially life-threatening bacterium in a 15-year-old girl with cystic fibrosis.

This old-time approach to battling bacterial infections might be worth another look in these days of antibiotic-resistant bacteria, a ne...

In what researchers are calling a groundbreaking achievement, an unmanned drone delivered a new kidney for a 44-year-old Baltimore woman.

On April 19, the aircraft delivered the donor kidney that was successfully transplanted by a surgical team at the University of Maryland Medical Center in Baltimore. The patient was discharged April 23. Before the operation, she had undergone eight ...

In a North American first, an anonymous living liver donation led to a rare paired living liver donor exchange in Canada last summer that saved the lives of two people with failing livers.

Kelly Bryan, 38, donated 70% of her liver to an adult stranger, Muhammad Khan, who needed a liver transplant. Then that recipient's wife, Hina Khan, donated more than half her liver to another s...

The world's first complete 3D printer-generated heart, made using the patient's own cells and materials, has been created in a lab.

Until now, success has been limited to printing only simple tissues without blood vessels.

"This is the first time anyone anywhere has successfully engineered and printed an entire heart replete with cells, blood vessels, ventricles and chambers...

Patients in dire need of an organ transplant can safely receive a new heart or lung from donors who have hepatitis C, a new clinical trial has shown.

By swiftly administering powerful antiviral drugs, doctors can prevent the organ recipient from contracting hepatitis C following their transplant, said lead researcher Dr. Ann Woolley. She's an infectious disease doctor with Brigham and...

Surgeons in Baltimore have performed the world's first kidney transplant in which both the living donor and the recipient are HIV-positive.

The success of the operation could potentially make organs more widely available to patients infected with the AIDS virus.

A 35-year-old Atlanta woman who contracted HIV as a newborn offered one of her kidneys to an HIV-positive stranger...

The chances of finding an unrelated bone marrow donor are higher for U.S. patients of European descent than for those of non-European descent, a new study finds.

A bone marrow transplant can sometimes help people with life-threatening blood cancers by replacing the patient's cells with healthy ones from a donor. A brother or sister with the same genetic markers as the recipient is the...

Sarah Bradley's second pregnancy was uneventful until 30 weeks, when she found herself swollen, breathless and unusually fatigued.

When her chest and left side also began to hurt a few weeks later, the then-27-year-old from Roswell, New Mexico, went to the emergency room. Tests revealed she was in heart failure.

Sarah was flown to a hospital in Albuquerque, where doctors...

Kristen Patton was settling in to feed her newborn on Christmas Eve as her three older children went to bed.

It was the holiday evening she had envisioned -- relaxed family time the day after coming home from the hospital following the birth of her daughter, Hattie.

Suddenly, unbelievable pain shot through Kristen's left jaw. It moved in a web-like pattern into her cheek, ...

Patients with kidney failure who are on dialysis or have received a transplant have a sharply higher risk of dying from cancer, Australian researchers report.

In fact, compared with people who don't have kidney failure, they have more than double the odds of cancer death. The odds are particularly high among patients aged 20 to 34, for whom the risk is 11 times higher, the researcher...

Given the choice of walking 3 miles or 1 mile, Amanda "Mandi" Tate always opts for the longer route at the Tampa Bay Heart Walk.

In 2015, her boyfriend Patrick Shelley and childhood friend Jessica Dosio joined her.

When Mandi ran off to grab something, Jessica asked Patrick what she'd been asking him for months: "When are you going to propose?"

"Actually," he s...