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Results for search "Alzheimer's".

29 Jul

HealthDay Now: Alzheimer’s Drug Approval Harms FDA’s Reputation

In a HealthDay Now interview, we spoke with Dr. G. Caleb Alexander, a professor at Johns Hopkins. He served on the FDA advisory committee that nearly unanimously advised against approving Biogen's controversial new Alzheimer's drug. Dr. Alexander discusses whether the FDA's reputation will take a permanent hit due to the drug's approval despite limited evidence of benefit.

29 Jun

4 Ways To Reduce Your Alzheimer’s Risk

Following a healthy lifestyle helps protect your brain and lower your risk of dementia

07 May

Eating A Mediterranean Diet Helps Prevent The Loss Of Brain Function, Study Finds

Following a diet rich in fruits, vegetables, fish and olive oil may protect your brain against protein build-up and shrinkage related to Alzheimer's disease, researchers say.

Health News Results - 213

Attention-deficit/hyperactivity disorder (ADHD) appears to be somehow linked to risk of dementia and Alzheimer's disease, a new multigenerational study has found.

Parents and grandparents of people with ADHD have a higher risk of Alzheimer's and dementia than people with no ADHD in their family, Swedish researchers said.

Specifically, parents of an ADHD child have a 34% higher risk ...

U.S. approval of the Alzheimer's drug Aduhelm is already mired in controversy. Now a new study finds that most Alzheimer's patients could not have taken part in clinical trials that led to the green light.

In June, the U.S. Food and Drug Administration gave accelerated approval to Aduhelm (aducanumab) for treating patients with mild cognitive impairment or mild dementia from Alzheimer's d...

It's more than just an annoyance: Long-term exposure to traffic and train noise may increase the risk of dementia and Alzheimer's disease, Danish researchers report.

The study authors said that more than 1,200 of Denmark's nearly 8,500 cases of dementia in 2017 may have resulted from exposure to noise, which means that reducing traffic noise might help prevent the thinking, memory and beh...

Older adults who take certain diabetes drugs may see a slower decline in their memory and thinking skills, a new study suggests.

Researchers in South Korea found that among older people who'd been having memory issues, those using diabetes drugs called DDP-4 inhibitors typically showed a slower progression in those symptoms over the next few years. That was compared with both diabetes-fre...

It's long been know that polluted can damage the heart and lungs, but new research finds that it's bad for your brain, too.

A long-term study by a Seattle team linked exposure to higher levels of fine particulate air pollution to an increased risk of dementia.

"We found that an increase of 1 microgram per cubic meter of exposure corresponded to a 16% greater hazard of all-cause dem...

Could a drug used to treat amyotrophic lateral sclerosis (ALS) help people with mild Alzheimer's disease?

The results of a small new study suggest the strategy could work.

Riluzole has been used for more than 20 years to slow the progression of ALS, commonly called Lou Gehrig's disease. This phase 2 study found that the drug slowed brain metabolic decline and had a positive effect o...

Death rates from Alzheimer's disease are particularly high in the rural United States, a preliminary study finds, highlighting a need for health care resources in traditionally under-served areas.

Researchers discovered that over the past two decades, rural areas in the Southeast have seen the highest death rates from Alzheimer's, at 274 per 100,000 people. That's about twice the rate as ...

COVID-19 can kill you. It can rob you of your breath, cause strange blood clots, and prompt side effects that last for months after you're over the initial infection.

It's also possible that COVID-19 might impact the human brain in ways that could promote the onset of Alzheimer's disease, a new study reports.

Severely ill COVID-19 patients display biological evidence of brain injury...

Something as simple as having a glass of orange juice in the morning or an apple at lunch could be one of the keys to protecting your brain health.

People who consumed just a half serving a day of foods high in a naturally occurring compound called flavonoids had a 20% lower risk of mental decline, according to a new study.

"We think it may have important public health i...

An outside advisor to the U.S. Food and Drug Administration's review of the controversial Alzheimer's drug Aduhelm is now speaking out, arguing that the approval was based on dodgy science and involved questionable collaboration between regulators and the drug's maker.

"I'm not surprised at the controversy because I think it's a horrible decision. I think the FDA got it wrong," said Dr. G...

While efforts to develop Alzheimer's medications have so far borne little fruit, new research highlights the therapeutic promise of two non-drug tools: light and sound.

According to a pair of small new studies, exposing Alzheimer's patients to an hour a day of carefully modulated light and/or sound appears, over time, to slow down the telltale brain degeneration that typifies disease prog...

Air pollution causes you to gasp and wheeze. Smog puts strain on your hearts and inflames your lungs.

Could dirty air also be costing you your brain health?

A trio of new studies finds that air quality appears linked to a risk of thinking declines and dementia, and bad air might even promote toxic brain proteins that are a hallmark of Alzheimer's disease.

"This is extremely ex...

The controversial new Alzheimer's drug Aduhelm is creating something of a civil war in medicine, as health networks, hospitals, insurers and individual doctors weigh impending discussions with patients about whether they should take the medication.

Many doctors believe the U.S. Food and Drug Administration "moved the goalposts" to approve Aduhelm (aducanumab) in early June, and they aren'...

A drug that eases hallucinations in people with Parkinson's disease may be able to do the same for those with dementia, a new clinical trial finds.

The medication, called Nuplazid (pimavanserin), is already approved in the United States for treating hallucinations and delusions related to Parkinson's.

The new study, published July 22 in the New England Journal of Medicine, ...

Dementia is largely a disease of old age, but a new study finds that up to 5% of all cases are among people in the prime of their lives.

Looking at 95 international studies, researchers estimated that nearly 4 million people worldwide are living with young-onset dementia -- cases that strike between the ages of 30 and 64.

In the United States, an estimated 175,000 people have the co...

Women on hormone replacement therapy (HRT) for menopause go on to have a 58% lower risk of Alzheimer's disease and other neurodegenerative conditions, a new study finds.

Although the study wasn't designed to prove cause and effect, the findings could point the way to new treatments for such diseases, according to the researchers.

"This is not the first study on the impact of hormone...

What's better -- a long life or quality of life?

New research suggests that people balance both when thinking about their desired life span, and fears of suffering dementia or chronic pain in old age tend to limit how long they want to live.

"Dementia tops the list of conditions where people would prefer to live shorter lives -- which is a particular challenge given the rapid incr...

Two major U.S. health systems say they will not administer the controversial new Alzheimer's drug Aduhelm.

The decisions by the Cleveland Clinic and Mount Sinai's Health System in New York City are the latest fallout from the U.S. Food and Drug Administration's widely criticized approval of the Biogen drug on June 7, The New York Times reported.

Many experts say there's no ...

An active mind in old age may delay Alzheimer's disease by up to five years, a new study suggests.

Activities like reading, writing letters, playing cards or doing puzzles may prolong brain health even for those in their 80s, researchers say.

"The key element is that you're processing information," said lead researcher Robert Wilson, a professor in the neurological sciences departme...

TUESDAY, July 13, 2021 (Healthday News) -- Medicare launched a formal process on Monday that will determine whether the agency will cover Aduhelm, the newly approved Alzheimer's drug whose high price tag and unproven benefits have prompted widespread controversy.

Medicare's announcement came the same day that leaders of two House committees that are investigating Aduhelm's approval asked ...

MONDAY, July 12, 2021 (Healthday News) -- The U.S. Food and Drug Administration's controversial approval of the Alzheimer's drug Aduhelm should be investigated by the Office of Inspector General (OIG), FDA Acting Commissioner Dr. Janet Woodcock has said.

The FDA approved Aduhelm even though an advisory panel of outside experts said there wasn't enough proof that the drug actually works. T...

The U.S. Food and Drug Administration on Thursday issued new prescribing rules for the controversial Alzheimer's medication Aduhelm that will likely limit its use.

When first approved a month ago, the FDA said Biogen's monthly IV drug was for all Alzheimer's patients. The agency now says the drug is appropriate for patients with early or mild Alzheimer's but that it has not been studied i...

THURSDAY, July 1, 2021 (Healthday News) -- The U.S. Food and Drug Administration's controversial approval of a new Alzheimer's drug, along with its high price, is now being investigated by two House committees.

"We have serious concerns about the steep price of Biogen's new Alzheimer's drug Aduhelm and the process that led to its approval despite questions about the drug's clinical benefi...

Dementia patients who have the same nurse for all of their home health care visits are a third less likely to be readmitted to the hospital, a new study finds.

"While continuity of nursing care may benefit every home health care patient, it may be particularly critical for people with dementia," said study co-author Chenjuan Ma. "Having the same person delivering care can increase familia...

Alzheimer's disease has no cure, but one expert says it may be possible to reduce the risks of developing the disease with healthy lifestyle changes.

There are two different types of Alzheimer's. Early-onset typically affects patients before age 65. Late-onset affects older adults.

"Early-onset dementia often is linked to genetics and can run in families," said Dr. Chen Zhao, a neur...

Most Americans with dementia are undiagnosed, which shows how important it is to screen and assess seniors for the disease, researchers say.

Their new analysis of data from a nationwide survey of about 6 million Americans aged 65 and older revealed that 91% of people with cognitive impairment consistent with dementia did not have a formal medical diagnosis of dementia or Alzheimer's disea...

FRIDAY, June 25, 2021 (Healthday News) -- Fresh on the heels of the U.S. Food and Drug Administration's approval of the controversial Alzheimer's drug Aduhelm, the maker of a second medicine that works in similar fashion said Thursday it hopes to apply for approval of its medication later this year.

Eli Lilly said findings from a mid-stage clinical trial of 272 patients with early Alzheim...

The brains of people who died from COVID-19 were remarkably similar to the brains of people who die from neurodegenerative diseases such as Alzheimer's and Parkinson's, showing inflammation and disrupted circuitry, researchers report.

"The brains of patients who died from severe COVID-19 showed profound molecular markers of inflammation, even though those patients didn't have any reporte...

An experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to save brain function.

In a Phase 2 clinical trial, the vaccine produced high levels of antibodies to target and attack free-floating tau proteins before they can form "tau tangles" that clog neurons and damage brain function. Tau tangles, ...

The U.S. Food and Drug Administration has approved the first new drug to treat Alzheimer's disease in nearly two decades, in a controversial decision that left the agency defending its reputation and its science.

Aduhelm (aducanumab) treats Alzheimer's by clearing out amyloid beta, a sticky protein known to form plaques in the brains of early-stage patients.

It is the first approved...

The first drug ever shown to slow the progression of Alzheimer's disease could be approved by the U.S. Food and Drug Administration on Monday, but experts say that approval will be surrounded by controversy.

In clinical trials, aducanumab showed a 22% reduction in the development of thinking and memory problems associated with Alzheimer's disease, according to a statement from the Alzheim...

The U.S. government and nonprofits are replacing drug companies as the main drivers of Alzheimer's disease research, two new studies show.

The findings are from an analysis of national data by Jeffrey Cummings, a research professor at the University of Nevada, Las Vegas School of Integrated Health Sciences.

In one study, his team found that the number of Alzheimer's clinical trials ...

For people worried about developing dementia due to their family history, a preliminary study offers some good news: A healthy lifestyle might curb your risk.

Researchers found that older adults with healthy habits had a lower risk of developing dementia, versus the less health-conscious -- even if a parent or sibling had suffered from the brain disease.

Lifestyle choices did not er...

Feelings of grief are expected after the loss of a loved one, but having those feelings when your loved one has a terminal illness is also real and can fluctuate over time, experts say.

Individuals can adjust to their emotional pain, according to a new study focusing on what is known as "pre-loss grief" observed at two points in time for people whose family members had advanced can...

A diet rich in vegetables, fruits, olive oil and fish -- the so-called Mediterranean diet -- may protect the brain from plaque buildup and shrinkage, a new study suggests.

Researchers in Germany looked at the link between diet and the proteins amyloid and tau, which are a hallmark of Alzheimer's but are also found in the brains of older people without dementia.

"These results contr...

That college degree may be useful in many ways, but new research suggests it probably won't keep your brain from shrinking with age.

Over the years, a number of studies have suggested that education might buffer people against age-related declines in memory and thinking. But those findings did not prove a cause-and-effect relationship.

In the new study, researchers asked whether peo...

Alzheimer's disease and traumatic brain injury appear to affect the brain in similar ways, according to a study that may point to new ways to identify people at high risk for Alzheimer's.

"These findings are the first to suggest that cognitive impairment following a traumatic brain injury is useful for predicting the magnitude of Alzheimer's-like brain degradation," said study author Andr...

Where you live could affect your brain health as you age, a new study claims.

Specifically, it found that middle-aged and older people in poorer neighborhoods showed more brain shrinkage and faster mental decline than those in affluent neighborhoods.

""Worldwide, dementia is a major cause of illness and a devastating diagnosis," said study author Dr. Amy Kind, of the University of W...

Don't forget to floss: New research adds to evidence linking gum disease with Alzheimer's disease.

The mouth is home to both harmful bacteria that promote inflammation and healthy, protective bacteria, the study authors explained.

In the new study, the researchers found that people who have more harmful than healthy gum bacteria were more likely to also have a protein marker for Al...

U.S. assisted living facilities often have activities to keep seniors socially engaged -- but a new study says they need to ensure that residents with dementia are not left out.

Researchers observed residents and staff at four assisted living communities over the course of a year.

They found that a few factors stood out as key to keeping residents with dementia socially and mentally...

Caring for a loved one with Alzheimer's disease can be mentally and physically exhausting, so you should take steps to manage and reduce stress, according to the Alzheimer's Foundation of America.

"Finding ways to manage and reduce stress is of paramount importance for every Alzheimer's caregiver. Untreated stress can lead to physical, mental and emotional caregiver burnout," Jennifer Ree...

Middle-aged folks who feel persistently lonely appear to have a nearly doubled risk of developing dementia or Alzheimer's disease, a new study reports.

If you take steps to counter your loneliness, however, you might actually reduce your dementia risk, the researchers found.

Dementia risk rose 91% in those who reported feelings of loneliness that persisted across two separate health...

When people die some cells in their brains go on for hours, even getting more active and growing to gargantuan proportions, new research shows.

Awareness of this activity, spurred on by "zombie genes," could affect research into diseases that affect the brain.

For the study, researchers analyzed gene expression using fresh brain tissue collected during routine surgery and found that...

Regular aerobic exercise increases blood flow to the brain, which may help slow mental decline in older adults, a new, small study suggests.

Researchers from University of Texas Southwestern Medical Center looked at 70 men and women diagnosed with mild cognitive impairment (MCI). This means there are slight changes to the brain that affect memory, decision-making or reasoning skills. In m...

A new study shows just how devastating a diagnosis of mental decline can be: Researchers found that rates of suicide rise sharply in the months after such news is delivered.

The study of almost 148,000 older U.S. Department of Veterans Affairs patients, mostly men, looked at diagnoses for mild cognitive impairment (MCI), which is often (but not always) a precursor to dementia.

"Risk...

If you're a 20-something who wants to stay sharp, listen up: A new study suggests poor health habits now may increase your risk of mental decline later in life.

Its authors say young adulthood may be the most critical time for adopting a healthy lifestyle in order to keep your brain sharp when you're older.

That's the upshot of an analysis of data from about 15,000 adults who were p...

About 7 out of 10 Alzheimer's patients wound up free of the brain plaques that are a hallmark of the disease after treatment with a potentially breakthrough experimental drug, clinical trial results show.

The drug, donanemab, also significantly slowed the patients' brain decline, according to findings published March 13 in the New England Journal of Medicine.

Donanemab diss...

Black and Hispanic Americans already face higher risks for dementia than the general population. Many also believe they'd get worse dementia care compared to white patients, according to a new Alzheimer's Association special report.

Older Black Americans are about twice as likely to have Alzheimer's or another form of dementia as older white people, and older Hispanics are about 1.5 times...

The ravages of Alzheimer's may strike later in women than men, but once it takes hold women tend to deteriorate far faster than men, according to a new study.

Something known as cognitive reserve helps the aging brain function better for longer, and researchers report that women appear to have more of it than men. But once the reserve runs out, mental decline in women speeds up.

"Wo...

People with Alzheimer's disease often have a history of depression or anxiety, which might mean an earlier emergence of memory and thinking problems, a preliminary study suggests.

Researchers found that of 1,500 Alzheimer's patients at their center, 43% had a history of depression, while almost one-third had a history of anxiety disorders.

Those patients also tended to be diagnosed ...

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